ICD-10 Diagnosis Code A69.22

Other neurologic disorders in Lyme disease

Diagnosis Code A69.22

ICD-10: A69.22
Short Description: Other neurologic disorders in Lyme disease
Long Description: Other neurologic disorders in Lyme disease
This is the 2019 version of the ICD-10-CM diagnosis code A69.22

Valid for Submission
The code A69.22 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Certain infectious and parasitic diseases (A00–B99)
    • Other spirochetal diseases (A65-A69)
      • Other spirochetal infections (A69)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code A69.22 is grouped in the following Diagnostic Related Group(s) (MS-DRG V35.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Bannwarth syndrome
  • Borrelia infection of central nervous system
  • Lyme mononeuritis multiplex
  • Lyme neuroborreliosis
  • Mononeuritis multiplex

Index of Diseases and Injuries
References found for the code A69.22 in the Index of Diseases and Injuries:

Information for Patients

Lyme Disease

Lyme disease is a bacterial infection you get from the bite of an infected tick. The first symptom is usually a red rash, which may look like a bull's eye. But not all people with Lyme disease have a rash. As the infection spreads to other parts of the body, you may have

  • A fever
  • A headache
  • Body aches
  • A stiff neck
  • Fatigue

Lyme disease can be hard to diagnose because many of its symptoms are like those of the flu and other diseases. And you may not have noticed a tick bite. Your health care provider will look at your symptoms and medical history to figure out whether you have Lyme disease. Lab tests may not always give a clear answer until you have been infected for at least a few weeks.

Antibiotics can cure most cases of Lyme disease. The sooner treatment begins, the quicker and more complete the recovery.

After treatment, some patients may still have muscle or joint aches and nervous system symptoms. This is called post-treatment Lyme disease syndrome (PTLDS). Long-term antibiotics have not been shown to help with PTLDS. However, there are ways to help with the symptoms of PTLDS, and most patients do get better with time.

NIH: National Institute of Allergy and Infectious Diseases

  • Lyme disease (Medical Encyclopedia)
  • Lyme disease antibody (Medical Encyclopedia)
  • Ticks and Lyme Disease: Symptoms, Treatment, and Prevention (Food and Drug Administration)


Lyme disease Lyme disease is an infectious disease caused by Borrelia burgdorferi bacteria. The bacteria are transferred to humans by tick bite, specifically by blacklegged ticks (commonly known as deer ticks). The condition is named for the location in which it was first described, the town of Lyme, Connecticut.If not treated with antibiotics, Lyme disease follows three stages: early localized, early disseminated, and late disseminated infection. A small percentage of individuals have symptoms that persist months or years after treatment, which is called post-treatment Lyme disease syndrome.A characteristic feature of Lyme disease, and the key feature of early localized infection, is a slowly expanding red rash on the skin (called erythema migrans) at the site of the tick bite; the rash is often bull's-eye shaped. Flu-like symptoms and enlarged lymph nodes (lymphadenopathy) are also early signs of infection. Most people who are treated at this stage never develop further symptoms.The early disseminated stage of Lyme disease occurs as the bacteria is carried throughout the body in the bloodstream. This stage occurs a few weeks after the tick bite. Signs and symptoms can include additional rashes on other parts of the body, flu-like symptoms, and lymphadenopathy. Some affected individuals develop neurologic problems (referred to as neuroborreliosis), such as paralyzed muscles in the face (facial palsy); pain, numbness, or weakness in the hands or feet; difficulty concentrating; or memory problems. Rarely, the heart is affected (Lyme carditis), causing a sensation of fluttering or pounding in the chest (palpitations) or an irregular heartbeat.The late disseminated stage of Lyme disease can occur months to years after the tick bite. The most common feature of this stage, Lyme arthritis, is characterized by episodes of joint pain and swelling, usually affecting the knees. In rare cases, the late disseminated stage also involves neurological problems.Individuals with post-treatment Lyme disease syndrome report ongoing exhaustion (fatigue), muscle and joint achiness, headache, or difficulty concentrating even after treatment with antibiotics, when there is no evidence of the bacteria in the body. Very rarely, individuals have joint pain and swelling for months or years after successful antibiotic treatment. This complication is called antibiotic-refractory Lyme arthritis.
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