ICD-10 Diagnosis Code F43.21


Adjustment disorder with depressed mood

Diagnosis Code F43.21

ICD-10: F43.21
Short Description: Adjustment disorder with depressed mood
Long Description: Adjustment disorder with depressed mood
This is the 2018 version of the ICD-10-CM diagnosis code F43.21

Valid for Submission
The code F43.21 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Mental and behavioural disorders (F00–F99)
    • Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders (F40-F48)
      • Reaction to severe stress, and adjustment disorders (F43)

Information for Patients


Mental Disorders

Also called: Mental illness

Mental disorders include a wide range of problems, including

  • Anxiety disorders, including panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and phobias
  • Bipolar disorder
  • Depression
  • Mood disorders
  • Personality disorders
  • Psychotic disorders, including schizophrenia

There are many causes of mental disorders. Your genes and family history may play a role. Your life experiences, such as stress or a history of abuse, may also matter. Biological factors can also be part of the cause. A traumatic brain injury can lead to a mental disorder. A mother's exposure to viruses or toxic chemicals while pregnant may play a part. Other factors may increase your risk, such as use of illegal drugs or having a serious medical condition like cancer.

Medications and counseling can help many mental disorders.

  • Adjustment disorder (Medical Encyclopedia)
  • Conversion disorder (Medical Encyclopedia)
  • Illness anxiety disorder (Medical Encyclopedia)
  • Somatic symptom disorder (Medical Encyclopedia)


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