ICD-10 Diagnosis Code G35

Multiple sclerosis

Diagnosis Code G35

ICD-10: G35
Short Description: Multiple sclerosis
Long Description: Multiple sclerosis
This is the 2018 version of the ICD-10-CM diagnosis code G35

Valid for Submission
The code G35 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Diseases of the nervous system (G00–G99)
    • Demyelinating diseases of the central nervous system (G35-G37)
      • Multiple sclerosis (G35)

Information for Medical Professionals

Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.
  • 340 - Multiple sclerosis

  • Acute relapsing multiple sclerosis
  • Benign multiple sclerosis
  • Chronic progressive multiple sclerosis
  • Congitive impairment due to multiple sclerosis
  • Dementia associated with multiple sclerosis
  • Dementia due to multiple sclerosis with altered behavior
  • Exacerbation of multiple sclerosis
  • Functional quadriplegia due to multiple sclerosis
  • Generalized multiple sclerosis
  • Malignant multiple sclerosis
  • Multiple sclerosis
  • Multiple sclerosis of the brainstem
  • Multiple sclerosis of the spinal cord
  • Primary progressive multiple sclerosis
  • Relapsing remitting multiple sclerosis
  • Remittent-progressive multiple sclerosis
  • Secondary progressive multiple sclerosis
  • Spinal demyelination

Index of Diseases and Injuries
References found for the code G35 in the Index of Diseases and Injuries:

Information for Patients

Multiple Sclerosis

Also called: MS

Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include

  • Visual disturbances
  • Muscle weakness
  • Trouble with coordination and balance
  • Sensations such as numbness, prickling, or "pins and needles"
  • Thinking and memory problems

No one knows what causes MS. It may be an autoimmune disease, which happens when your immune system attacks healthy cells in your body by mistake. Multiple sclerosis affects women more than men. It often begins between the ages of 20 and 40. Usually, the disease is mild, but some people lose the ability to write, speak, or walk.

There is no single test for MS. Doctors use a medical history, physical exam, neurological exam, MRI, and other tests to diagnose it. There is no cure for MS, but medicines may slow it down and help control symptoms. Physical and occupational therapy may also help.

NIH: National Institute of Neurological Disorders and Stroke

  • Cerebral spinal fluid (CSF) collection (Medical Encyclopedia)
  • CSF oligoclonal banding (Medical Encyclopedia)
  • Daily bowel care program (Medical Encyclopedia)
  • Multiple sclerosis (Medical Encyclopedia)
  • Multiple sclerosis - discharge (Medical Encyclopedia)


Multiple sclerosis Multiple sclerosis is a condition characterized by areas of damage (lesions) on the brain and spinal cord. These lesions are associated with destruction of the covering that protects nerves and promotes the efficient transmission of nerve impulses (the myelin sheath) and damage to nerve cells. Multiple sclerosis is considered an autoimmune disorder; autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs, in this case tissues of the nervous system.Multiple sclerosis usually begins in early adulthood, between ages 20 and 40. The symptoms vary widely, and affected individuals can experience one or more effects of nervous system damage. Multiple sclerosis often causes sensory disturbances in the limbs, including a prickling or tingling sensation (paresthesia), numbness, pain, and itching. Some people experience Lhermitte sign, which is an electrical shock-like sensation that runs down the back and into the limbs. This sensation usually occurs when the head is bent forward. Problems with muscle control are common in people with multiple sclerosis. Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty walking, or poor bladder control. Multiple sclerosis is also associated with vision problems, such as blurred or double vision or partial or complete vision loss. Infections that cause fever can make the symptoms worse.There are several forms of multiple sclerosis: relapsing-remitting MS, secondary progressive MS, primary progressive MS, and progressive relapsing MS. The most common is the relapsing-remitting form, which affects approximately 80 percent of people with multiple sclerosis. Individuals with this form of the condition have periods during which they experience symptoms, called clinical attacks, followed by periods without any symptoms (remission). The triggers of clinical attacks and remissions are unknown. After about 10 years, relapsing-remitting MS usually develops into another form of the disorder called secondary progressive MS. In this form, there are no remissions, and symptoms of the condition continually worsen.Primary progressive MS is the next most common form, affecting approximately 10 to 20 percent of people with multiple sclerosis. This form is characterized by constant symptoms that worsen over time, with no clinical attacks or remissions. Primary progressive MS typically begins later than the other forms, around age 40.Progressive relapsing MS is a rare form of multiple sclerosis that initially appears like primary progressive MS, with constant symptoms. However, people with progressive relapsing MS also experience clinical attacks of more severe symptoms.
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